How might little lifestyle adjustments lead to increased longevity? People refer to these as “Life hacks” and “Hunger gains.” Is it really that simple to eat less and live longer? Calorie-restricted diets have been shown in certain studies to increase life spans in animal models by up to 300%. This calorie restriction often contains 50% fewer calories than a typical diet, and people’s food preferences can have a significant impact on their health.

According to the Rate-of-Living theory, an organism’s lifespan decreases with increasing metabolic rate. Comparing the metabolism of a mouse and a tortoise can help. Max Rubner first developed it in 1908 in response to observations that larger animals outlast smaller ones and have slower metabolisms. After sorting through the data, they came to the conclusion that a formula for scaling lifetime vs. metabolic rate may be used to estimate the basal metabolic rate with accuracy.


The researchers evaluated slightly over 200 individuals, ages 21 to 50, over two years. All had taken part in the clinical trial known as CALERIE—Comprehensive Assessment of Long-Term Effects of Reducing Energy Intake.

All of the subjects fell into the healthy, non-obese category with a body mass index ranging from 22.0 to 27.9.

The CALERIE experiment had already demonstrated a decrease in the cardiometabolic risk variables in this group, including blood pressure and cholesterol levels.

oxidative stress's side effects


The immune system’s ability to function depends in part on body fat, often known as adipose tissue. When improperly triggered, some immune cells in this tissue might trigger inflammatory reactions.

They discovered alterations in adipose tissue gene expression, with some genes repressed in individuals who had restricted diets. To determine if these modifications were responsible for the positive effects of calorie restriction, the researchers looked into these changes further.


Harman’s Free Radical Theory of Aging developed in the 1950s, postulated that the buildup of free radical damage in the body causes organisms to age over time, provided evidence. It also demonstrated that free radicals are frequently produced by metabolic activities, particularly those occurring in the mitochondria. Another way to put it is that when you eat calories, your body uses oxidative phosphorylation to break them down after digestion and absorption. Adenosine triphosphate (ATP), the substance our body utilizes for fundamental metabolic activity, and free radicals are produced by this crucial process.

Free radicals are oxygen-containing molecules with an unbalanced amount of electrons, which makes it simple for them to interact with other molecules and leads to the body’s oxidation, which is characterized by long chemical chains. Cells and entire organisms age as a result of oxidative stress.

Reactive oxygen species (free radicals) damage DNA and alter the protein and lipid composition of the cell when they build up. In the end, the cell stops functioning and dies. The body ages and the tissues deteriorate over time. Physical indications of aging can occur because of this oxidative stress’s effects on the body’s cellular repair processes.

Consider the following factors that affect how old you appear :

  • Skin tone
  • Elasticity
  • Liver function
  • Muscle/tendon function, repair, and maintenance

Calorie-restricted diet


Oxidative stress can contribute to the development of cancer, diabetes, cardiovascular disorders like atherosclerosis and stroke, chronic fatigue syndrome, asthma, male infertility, and common neurodegenerative diseases like Alzheimer’s and Parkinson’s disease in addition to aging-related symptoms.


We can always return to the subject of nutrition and exercise. we are consuming fewer processed foods, especially those high in carbohydrates and fats while maintaining a balanced, healthful diet rich in fruit and vegetables. Regular exercise should include periods of prolonged heart rate elevation. You should also give up smoking and lessen stress.

If you are experiencing comparable symptoms and if it fails to improve with treatment or remedies and instead becomes more severe or incapacitating, see a doctor at Specialty Care Clinics and contact us at (469) 545-9983.

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